Designs, such Placemats as the Eff-Tox, OBD (optimal biological dose), STEIN (simple efficacy toxicity interval), and TEPI (toxicity efficacy probability interval) designs, have been proposed to determine the optimal dose of a new oncology drug using both efficacy and toxicity.The goal of these designs is to select the optimal drug dose for further
The passive mobilization of the hand joints by means of dedicated equipment accelerates patient recovery Placemats and decreases significantly the costs of therapy.For this reason, research and development of such equipment is essential.Important reductions in the development cycle duration of such equipment can be achieved by means of a specific t
Background and objective: Each year millions of tons ALL IN ONE LIGHTLY SWEET of halal food waste are excreted into the environment.In addition to causing the phenomenon of global warming, it also causes economic losses to halal food industrial units.In the last two decades, globalization, lifestyle and consumer preferences, and market dynamics hav